Smoked Turkey Grilled Cheese

Featured in: Simple Weeknight Meals

A delicious American sandwich combining smoked turkey breast with sharp cheddar cheese and a homemade cranberry-mustard spread, grilled until the cheese melts and bread turns golden. Takes just 18 minutes from start to finish and serves two.

The cranberry sauce mixed with Dijon mustard creates a sweet and tangy flavor profile that perfectly complements the savory smoked turkey and rich cheddar. Cooked in a skillet over medium heat for 3-4 minutes per side until golden brown.

Updated on Sun, 18 Jan 2026 16:39:00 GMT
Golden toasted sourdough bread layered with smoked turkey, sharp cheddar, and tangy cranberry spread for a savory grilled cheese. Save
Golden toasted sourdough bread layered with smoked turkey, sharp cheddar, and tangy cranberry spread for a savory grilled cheese. | hyperladle.com

My neighbor knocked on my door one November afternoon holding a Tupperware full of leftover smoked turkey. She was leaving town and didn't want it to go to waste. I wasn't sure what to do with it until I remembered the half jar of cranberry sauce still sitting in my fridge from Thanksgiving. That's when this sandwich was born, standing at my counter with butter in one hand and cheese in the other, improvising what turned out to be one of my favorite lunches ever.

I started making this sandwich every time I had friends over for casual lunches. One of them called it 'holiday leftovers without the guilt,' which made me laugh because it's true. The smell of butter browning on sourdough always brought people into the kitchen before I even finished cooking. It became our unofficial fall tradition, even when Thanksgiving was months away.

Ingredients

  • Hearty sandwich bread: Sourdough is my go to because it gets perfectly crisp on the outside while staying soft enough to bite through, and whole wheat adds a nutty flavor that works surprisingly well with turkey.
  • Smoked turkey breast: The smokiness is what makes this sandwich sing, so don't swap it for plain deli turkey unless you have to.
  • Sharp cheddar cheese: Sharp cheddar has enough bite to stand up to the sweet cranberry, but if you want something creamier, smoked Gouda melts like a dream.
  • Cranberry sauce: Whole berry gives you little bursts of texture, but jellied works just fine and spreads more evenly if that's what you've got.
  • Dijon mustard: Just a teaspoon is enough to add a subtle kick without overpowering the sweetness of the cranberry.
  • Unsalted butter: Softened butter spreads easily and toasts the bread to that perfect golden brown without burning.

Instructions

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Make the cranberry spread:
In a small bowl, stir together the cranberry sauce and Dijon mustard until they're fully combined. This little mix is what ties the whole sandwich together, so don't skip it.
Butter the bread:
Lay out your four slices of bread and spread softened butter on one side of each slice. Make sure the butter reaches the edges so every bite gets crispy.
Assemble the filling:
Flip two slices over so the buttered side is down, then spread the cranberry mixture on the unbuttered side. Layer the smoked turkey and cheese on top, being generous but not so much that it all squishes out when you press down.
Close the sandwiches:
Top each sandwich with the remaining bread slices, buttered side facing out. Press gently so everything sticks together.
Heat the skillet:
Place a large skillet or griddle over medium heat and let it warm up for a minute or two. If it's too hot, the bread will burn before the cheese melts, so medium is key.
Grill the sandwiches:
Place both sandwiches in the skillet and cook for 3 to 4 minutes on the first side, pressing gently with a spatula. Flip carefully and cook the other side until the bread is golden and the cheese has fully melted.
Rest and serve:
Remove the sandwiches from the pan and let them rest for a minute so the cheese sets slightly. Slice in half and serve while they're still warm and gooey.
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A close-up of the Smoked Turkey Grilled Cheese sandwich, melted cheddar oozing from between crispy golden-brown bread slices. Save
A close-up of the Smoked Turkey Grilled Cheese sandwich, melted cheddar oozing from between crispy golden-brown bread slices. | hyperladle.com

One rainy Saturday, I made this sandwich for my sister who was feeling homesick. She took one bite and her whole face lit up. She said it tasted like the day after Thanksgiving, but better because there was no cleanup and no awkward family debates. We ended up eating three rounds of these sandwiches that afternoon, laughing and catching up while the rain drummed on the windows.

Choosing Your Bread

The bread you pick really does matter here. Sourdough gives you that tangy contrast to the sweet cranberry, and it crisps up beautifully without getting too hard. Whole wheat adds a heartier, slightly nutty flavor that makes the sandwich feel more substantial. I've also used a good country white loaf when that's all I had, and it worked just fine. Just avoid anything too soft or thin, because it won't hold up to the filling or get that satisfying crunch.

Variations Worth Trying

Once you've made this sandwich a few times, it's fun to play around with it. Swiss cheese makes it taste more like a classic turkey melt, and Gruyère adds a fancy, nutty richness that's perfect if you're trying to impress someone. I've tucked in a handful of baby spinach before, and it added a fresh bite without changing the flavor too much. One friend of mine swears by adding thin apple slices, which sounds weird but actually works because of the sweet and savory balance.

What to Serve Alongside

This sandwich is filling enough to stand on its own, but it pairs beautifully with a simple green salad dressed in a light vinaigrette. The acidity from the dressing cuts through the richness of the cheese and butter. Sweet potato fries are another great option if you want something a little heartier and comforting. I've also served it with a cup of tomato soup when the weather turns cold, and it feels like the ultimate cozy lunch.

  • A handful of kettle cooked chips adds a nice salty crunch if you don't want to cook anything extra.
  • Pickles on the side, especially dill or bread and butter, give you a tangy palate cleanser between bites.
  • If you have any cranberry spread left over, it's great as a dip for crackers or spread on a turkey wrap the next day.
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The Smoked Turkey Grilled Cheese features toasted whole wheat bread with melted cheddar and a vibrant layer of cranberry spread. Save
The Smoked Turkey Grilled Cheese features toasted whole wheat bread with melted cheddar and a vibrant layer of cranberry spread. | hyperladle.com

This sandwich has become my go to whenever I want something that feels indulgent but doesn't require much effort or time. It reminds me that sometimes the best recipes come from happy accidents and a willingness to throw together whatever's in the fridge.

Recipe FAQs

Can I prepare the cranberry spread ahead of time?

Yes, the cranberry-mustard spread can be made up to 2 days in advance and stored in an airtight container in the refrigerator.

What bread works best for this sandwich?

Hearty sandwich breads like sourdough or whole wheat are recommended for their structure and flavor. They hold up well to grilling and the toppings without becoming soggy.

Can I use different cheese varieties?

Absolutely. Swiss, Gruyère, or smoked Gouda work wonderfully as substitutes for sharp cheddar, each offering unique flavor profiles.

How do I prevent the bread from burning while the cheese melts?

Cook over medium heat and press gently with a spatula. If needed, reduce heat slightly and cover the skillet briefly to help the cheese melt faster before the bread browns too much.

What are good side dishes to serve with this sandwich?

Light salads, sweet potato fries, or pickled vegetables complement the richness well. A simple green salad or coleslaw helps balance the savory and sweet flavors.

Can I add vegetables to this sandwich?

Yes, baby spinach or arugula add a fresh element. Thin tomato slices or caramelized onions also work well with the smoked turkey and cranberry spread.

Smoked Turkey Grilled Cheese

Smoked turkey, sharp cheddar, and cranberry spread melted between golden toasted bread slices.

Prep Time
10 mins
Time to Cook
8 mins
Complete Time
18 mins
Recipe by Victoria Thompson


Skill Level Easy

Cuisine American

Makes 2 Portions

Diet Details None specified

What You'll Need

Sandwich

01 4 slices hearty sandwich bread, sourdough or whole wheat
02 4 oz smoked turkey breast, thinly sliced
03 4 oz sharp cheddar cheese, sliced or shredded

Cranberry Spread

01 3 tablespoons cranberry sauce, whole berry or jellied
02 1 teaspoon Dijon mustard

For Grilling

01 2 tablespoons unsalted butter, softened

Directions

Step 01

Prepare Cranberry Spread: Combine cranberry sauce and Dijon mustard in a small bowl, mixing thoroughly until evenly blended.

Step 02

Butter the Bread: Lay out all bread slices and spread a thin layer of butter on one side of each slice. Place buttered sides down on work surface.

Step 03

Assemble First Layer: Spread cranberry mixture evenly on the unbuttered side of two bread slices.

Step 04

Add Fillings: Layer smoked turkey and cheddar cheese on top of the cranberry spread.

Step 05

Close Sandwiches: Top each sandwich with the remaining bread slices, buttered side facing outward.

Step 06

Heat Cooking Surface: Heat a large skillet or griddle over medium heat until evenly preheated.

Step 07

Grill Sandwiches: Place sandwiches in the skillet and cook for 3 to 4 minutes per side, pressing gently, until bread is golden brown and cheese has melted completely.

Step 08

Rest and Serve: Remove sandwiches from pan and let rest for 1 minute. Slice diagonally and serve warm.

Gear Needed

  • Skillet or griddle
  • Spatula
  • Small mixing bowl
  • Bread knife

Allergy Notes

Review every ingredient for allergens and talk to your doctor if unsure.
  • Contains gluten from bread
  • Contains dairy including butter and cheese
  • May contain mustard
  • Contains poultry

Nutrition Details (per portion)

Offered for reference only—please check with a healthcare professional for diet advice.
  • Energy: 420
  • Fats: 20 grams
  • Carbohydrates: 36 grams
  • Proteins: 24 grams